beta Amyloid anticorps (C-Term)
Aperçu rapide pour beta Amyloid anticorps (C-Term) (ABIN614817)
Antigène
Voir toutes beta Amyloid (Abeta) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Séquence
- GLMVGGVV
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Specificité
- This antibody recognizes the C-terminal peptide of beta amyloid peptide 40, and full length beta amyloid peptide 40.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein G affinity chromatography
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Immunogène
- C-terminal amino acid sequence of human beta amyloid peptide 40, conjugated with KLH
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore with Double distillated water is recommended to adjust the final concentration to 1.0 mg/mL.
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Buffer
- 0.01 M PBS pH 7.2
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store (in aliquots) at -20 °C.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Autre désignation
- Amyloid beta
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Sujet
- Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.
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ID gène
- 351
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Pathways
- Inflammasome
Antigène
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